The purposes of this study were 1) to develop a Computer-Assisted Instruction (CAI) with 80/80 of effective criteria for using in class of business operation registration and business taxes, 2) to compare learning achievement between before using CAI and after, 3) to compare learning achievement after using CAI with the criterion, 4) to study the satisfaction of students to CAI in Sriwattana techological college. The samples were 28 students of the vehicle engineering certification program in second semester of the academic year 2011. The research tools were lessons of CAI student management plan, learning achievement test, satisfaction test, statistical measurements were mean, standard deviation and t-test. The results were found as follows.
	1. CAI is effective 86.73/82.32 that more than the reference criterion at 80/80
       	2. After using CAI in class of business operation registration and business taxes, the learning achievement of students was higher than before using CAI (p=.01)
     	3. After using CAI in class of business operation registration and business taxes, the learning achievement of students was more than the reference criterion (>60%) at .01 significant level. 
       	4. The mean value of satisfaction of students to CAI was 4.32 that high satisfaction 
