The purposes of this study were to investigate the academic leadership of school principals, national quality assurance operation in schools, and also the relationship between academic leadership of school principals and national quality assurance operation in schools under the Office of Chachoengsao Primary Education Service, Area 1. The samples consisted of 448 teachers and principals. The instrument for collecting data was a questionnaire. 	The statistics used for the data analysis were percentage, mean, standard deviation and Pearsons Product Moment Correlation Coefficient.
             The research results were as follows:
              1. The academic leadership of school principals under the Office of Chachoengsao Primary Education Service, Area 1, as a whole, was at a high level, ranking by the mean scores from high to low; students learning assessment, perspective on trend of curriculum change, planning for teachers professional growth development, and project of management for special student.                
 	    2. The national quality assurance operation in schools under the Office of Chachoengsao Primary Education Service Area, 1, as a whole, was at a high level, ranking by the mean scores from high to low; schools standard educations, strategic planning, operation with strategic planning, and to continuous quality improvement.  
             3. The relationship between academic leadership of school principals and national quality assurance operation in schools under the Office of Chachoengsao Primary Education Service, Area 1 was positively (rxy=.844) significant different at the level of .05.     
